Background :
@EN Psoriasis is a dynamic process, both clincally and histopathologically. There is wide spectrum of histological change recognizable in psoriatic lesions.
@ES Objective :
@EN We attempted to clarify the histological features in psoriasis by quantitative sudies.
@ES Methods :
@EN We reviewed the clinical charts, photographs and skin biopsy slides of 106 patients who were diagnosed as psoriasis clinically or histopathologically between March, 1990 and August, 1994 at the Department of Dermatology, Korea University
Hospital.
The 12 histopathologic features of psoriasis were listed and examined whether these features were listed and examined whether these features were seen or not in each section. And if seen, then the features were scored 0 1. The sum of score in
each
section could range from 0 to 12.
@ES Results :
2EN 1. 72 of 106 patients wee psoriasis vulgaris. In other patients. The clinical forms of psoriasis were guttate psoriasis, pustulosis palmoplantaris, and generaliszed pustular psoriasis.
2. The average score of histopathologic features seen in each section were 8.11±2.11.
3. Sections commonly showed club shaped rete ridges, elongation and edema of the dermal papillae, perivascular mononuclear infiltrate in the upper dermis, absent grasnular layer, parakeratosis, suprapapillary plate thinning, mitosis above basal
cell
layer, and dilated tortuous blood vessels. The observed frequency of Munro microabscess, spongiform pustrle, and dilated tirtuous blood vessels were significantly lower in psoriasis vulgaris than in other clinical forms(p<0.05).
@ES Conclusion :
@EN This study showed that the histologic picture of psoriasis varied with the clinical forms. In each section seen, the observed frequncy of Munro microabscess and spongiform pustule was relatively low. (Kor J Dermatol 1996;34(4) : 580~584)
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